Celebrating the discovery of mutated CALR
Celebrating the discovery of mutated CALR
What is
essential
thrombocythemia
(ET)?
Most commonly diagnosed in women over the age of 50, ET is associated with a proliferation of platelet precursors in the bone marrow and complications frequently include blood clotting and/or bleeding.
What is
polycythemia vera
(PV)?
The disease is most common in men over the age of 60, but anyone can develop PV. PV patients typically experience an elevated red blood cell count, an elevated platelet count and an enlarged spleen, especially over time.
MF is a chronic blood cancer in which excessive scar tissue forms in the bone marrow and impairs its ability to produce normal blood cells.
What is
myelofibrosis
(MF)?
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What GLP-1 Drugs Reveal About MPNs, Inflammation, and Cancer Risk
MPN NEWS | July 23, 2025
What GLP-1 drugs reveal about MPNs, inflammation, and cancer risk A surprising link between inflammation, clonal blood stem cells, and a blockbuster drug opens new questions in blood cancer research. In recent years, glucagon-like peptide-1 receptor agonists (GLP-1RAs) — the class of drugs that includes Ozempic, Wegovy, and others — transformed care for type 2… Read More »What GLP-1 Drugs Reveal About MPNs, Inflammation, and Cancer Risk
How to train your AI model: Dr. Daniel Royston’s quest to decode the bone marrow
MPN NEWS | July 23, 2025
What do megakaryocytes, machine learning, and a team of Oxford scientists have in common? They’re all part of Dr. Daniel Royston’s mission to teach computers how to see what pathologists might miss — the secret signs of fibrosis hiding in the bone marrow. In this month’s Researcher Spotlight, step inside a one-of-a-kind laboratory where engineers… Read More »How to train your AI model: Dr. Daniel Royston’s quest to decode the bone marrow
How to explain MPNs to children
MPN NEWS | June 30, 2025
Explaining a chronic cancer like an MPN to a child can feel overwhelming — especially when the symptoms aren’t always visible. In this new article, pediatric psychologist Dr. Joanna Patten shares expert advice on what to say and how to say it. Learn why late is better than never and how honest, age-appropriate conversations help… Read More »How to explain MPNs to children
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