Celebrating the discovery of mutated CALR
What is
essential
thrombocythemia
(ET)?
Most commonly diagnosed in women over the age of 50, ET is associated with a proliferation of platelet precursors in the bone marrow and complications frequently include blood clotting and/or bleeding.
Learn more about ETWhat is
polycythemia vera
(PV)?
The disease is most common in men over the age of 60, but anyone can develop PV. PV patients typically experience an elevated red blood cell count, an elevated platelet count and an enlarged spleen, especially over time.
Learn more about PVWhat is
myelofibrosis
(MF)?
MF is a chronic blood cancer in which excessive scar tissue forms in the bone marrow and impairs its ability to produce normal blood cells.
Learn more about MFEvery patient experience is unique and provides new clues for researchers and clinicians.
In our 24-year history, MPNRF has contributed to some of the most influential MPN research discoveries.
Engage with us to ensure that new therapies have the maximum impact on patient outcomes and quality of life.
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Julie and her family joined team MPN and created HikeMF to join the fight against MPNs.
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October call out: Candy caution!
MPN NEWS | October 28, 2024
The sweet dilemma: balancing sugar intake and cancer risk this halloween Over the last 30 years, our consumption of sugar-laden beverages and processed foods has skyrocketed (Ma et al., 2022). While sugar itself isn’t inherently carcinogenic, the conditions it creates—like inflammation and metabolic dysfunction—set the stage for cancer to thrive. Chronic inflammation plays a significant… Read More »October call out: Candy caution!
Dr. Robert Kralovics, PhD Research Profile
MPN NEWS | October 25, 2024
Profile: Dr. Robert Kralovics, PhDMedical University of Vienna Harnessing the Immune System: Dr. Robert Kralovics’ Groundbreaking MPN Research Dr. Robert Kralovics is known for his relentless focus on unraveling the mysteries of myeloproliferative neoplasms (MPNs) —a family of rare blood cancers. As he admits, “I’ve been told I’m absent-minded because if someone suddenly talks to… Read More »Dr. Robert Kralovics, PhD Research Profile
Do you know your mutations? Genetics crossword
MPN NEWS | October 4, 2024
Do you know about mutations? Instructions: New genes and proteins are being discovered every year in the landscape of MPN research. Put your genetic know-how to the ultimate test with this advanced-level MPN crossword puzzle. Answers may include gene acronyms, mutations, and numbers, but no hyphens. You can find these answers below. Answers: Sources: Guglielmelli, P.,… Read More »Do you know your mutations? Genetics crossword
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