News & articles

  • How MPNs progress to AML and how to stop it

    Thrive Award Spotlight: John Crispino, St. Jude Children’s Research HospitalCo-PI – Ayalew Tefferi, Mayo Clinic, MN Aberrant Megakaryopoiesis in the MPNs According to Leukemia & Lymphoma Society, although MPN patients can be stable for decades, they face a significant risk of having their disease advance to a more immediately life-threatening blood cancer, acute myeloid leukemia… Read More »How MPNs progress to AML and how to stop it

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    Caregiver Brings Unique Perspective to MPNRF Patient Impact Council

    Kyle Bonder                                                                                                           … Read More »Caregiver Brings Unique Perspective to MPNRF Patient Impact Council

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    Learning More About MPN Cell Metabolism to Help Identify Novel Points of MPN Therapy

      Shannon Elf, PhD,    University of Utah  Huntsman Cancer Institute The metabolic landscape of MPNs is an extremely understudied area in the field. Solid tumor treatment has benefited tremendously from studying cellular metabolism in a number of cancers, and Dr. Shannon Elf, a junior investigator at University of Chicago, believes the same can be… Read More »Learning More About MPN Cell Metabolism to Help Identify Novel Points of MPN Therapy

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    What’s Next?

    The world of myeloproliferative neoplasms (MPNs) has witnessed a surge in scientific breakthroughs. From detecting genetic drivers as early as in the fetus to the unprecedented pace of new drug approvals, the momentum is changing how this family of blood cancers is understood and managed. Increased attention and industry investment have led to a growing number of treatment… Read More »What’s Next?

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    Our Own MPN Heroes

    We celebrate two members of our Board of Directors recently named MPN Heroes during the Annual Meeting of the American Society of Hematology (ASH). Dr. Andrew Schafer is director of the Richard T. Silver, M.D. MPN Center at Weill Cornell in NYC and a valued scientific advisor to MPN Research Foundation for many years. https://www.youtube.com/watch?v=9_yNLqJKHJU… Read More »Our Own MPN Heroes

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    MPN news to expect at ASH 2023

    Each year at the Annual Meeting of The American Society of Hematology (ASH), there are more MPN research and clinical trial reports. This year, some unique highlights include 16 topics we find notable, along with many others with a potential connection to MPNs.  Artificial intelligence (AI) to differentiate between essential thrombocythemia and prefibrotic primary myelofibrosis. … Read More »MPN news to expect at ASH 2023

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    Investigation of IL-1RAP in Myeloproliferative Neoplasms: Potential Novel Anti-leukemic Therapy

    Thrive Award Spotlight : Idoroenyi Amanam, MD Using our own immune system to treat cancers has become a reality for many solid and blood cancers. “It’s an ideal therapy, as it’s our own specialized system that helps treat abnormal cells,” according to Idoroenyi Amanam, MD, of City of Hope. For MPNs, there is a need… Read More »Investigation of IL-1RAP in Myeloproliferative Neoplasms: Potential Novel Anti-leukemic Therapy

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    2024-2026 Patient Impact Council Announced

    An MPNRF Patient Impact Council recently launched to actively advocate for the patient voice and perspective in all aspects of our work to promote research advances and therapies with meaningful patient benefits.    Created with very clear objectives and activities, the council includes individuals representing diversity in MPN experiences, diagnosis, skills, community connections, geographic locations, and… Read More »2024-2026 Patient Impact Council Announced

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    Dissecting and Targeting Transcriptional and Epigenetic Regulation in Advanced Myelofibrosis

    Thrive Award Spotlight : Iannis Aifantis, PhD “Our work has previously focused on other types of blood cancer, including myeloid and lymphoid leukemias,” says Iannis Aifantis, PhD, of NYU Langone. “A key aspect of the pathogenesis of myelofibrosis (MF) is the abnormal creation of blood outside the bone marrow,” for instance in the spleen. “Our… Read More »Dissecting and Targeting Transcriptional and Epigenetic Regulation in Advanced Myelofibrosis

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    2024 MPN Challenge: Request for Applications Open

    As of November 6th, 2023, the MPN Research Foundation has opened the MPN Challenge™ funding cycle. Please click here for further details on eligibility, proposal guidelines, and deadlines. Proposals are due January 30th, 2024.   

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