Driving groundbreaking research. Improving lives.
Helping people with an MPN live a better quality of life as we work toward answers to prevention, progression and a cure for polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF) – blood cancers collectively known as myeloproliferative neoplasms.
What is Primary Myelofibrosis (MF)?
Primary Myelofibrosis (MF)
PMF is a chronic blood cancer in which excessive scar tissue forms in the bone marrow and impairs its ability to produce normal blood cells.
What is Essential Thrombocythemia (ET)?
Essential Thrombocythemia (ET)
Most commonly diagnosed in women over the age of 50, ET is associated with a proliferation of platelet precursors in the bone marrow and complications frequently include blood clotting and/or bleeding.
What is Polycythemia Vera (PV)?
Polycythemia Vera (PV)
The disease is most common in men over the age of 60, but anyone can develop PV. PV patients typically experience an elevated red blood cell count, an elevated platelet count and an enlarged spleen, especially over time.
Recent News
MPN NEWS | March 15, 2025
MPN Research Foundation (MPNRF) and Canadian MPN Research Foundation (CMPNRF) launch collaboration to improve outcomes for MPN patients. MPN Research Foundation and Canadian MPN Research Foundation are pleased to announce a new collaboration focused on improving outcomes for myeloproliferative neoplasm (MPN) patients in the U.S., Canada, and beyond. The goal of the strategic initiative is… Read More »MPN Research Foundation (MPNRF) and Canadian MPN Research Foundation (CMPNRF) launch collaboration to improve outcomes for MPN patients
MPN NEWS | January 27, 2025
Trouble in the neighborhood: How one type of chromosome abnormality is more common than previously thought A recent study by Dr. Vesna Najfeld and her team brings fresh insights into myelofibrosis (MF), a type of myeloproliferative neoplasm (MPN). Their work highlights the importance of closely tracking genetic changes over time and suggests that changes around… Read More »Trouble in the neighborhood: How one type of chromosome abnormality is more common than previously thought
A wedding with a cause: How Adam and Jenny transformed tradition into purpose
MPN NEWS | January 27, 2025
A wedding with a cause: How Adam and Jenny transformed tradition into purpose When Jenny Applequist was diagnosed with a myeloproliferative neoplasm (MPN) in 2019, it marked the beginning of a transformative journey. “I felt a flood of emotions when I was first diagnosed,” Jenny shared. “I was still in denial for years.” Over time,… Read More »A wedding with a cause: How Adam and Jenny transformed tradition into purpose

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Julie and her family joined team MPN and created HikeMF to join the fight against MPNs.
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