Robert Kralovics, PhD

Austrian Academy of Sciences, Vienna

“Deciphering the Genetic Complexity of Myeloproliferative Disorders”

Research results: Discovery of CALR genetic mutation for MPNs (December 2013)

Shaoguang Li, MD PhD

University of Massachusetts Medical School

“Identification of Alox5 as a Potential Target Gene for the Treatment of Polycythemia Vera” – MF Challenge 2012

“My research focuses on identifying novel target genes in PV-initiating cells for developing curative therapeutic strategies for MPNs. We have discovered some promising candidate genes to be further tested functionally.” Click here to continue…

Wei Tong, PhD

Children’s Hospital of Pennsylvania

“K63 Ubiquitination in JAK2 Signaling and Myeloproliferative Neoplasms” – New Investigator grant program

“My research has identified new signaling molecules that impinge on JAK2 activity. Several of these in their own right might represent new therapeutic targets. Pharmacologic compounds that associate with these molecules may be used to modulate the JAK2 pathway when used alone or in combination with known JAK2 inhibitors that are in clinical trials already.” Click here to read more…

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